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Friday, January 25, 2019

Prescriptions for Ritalin drop sharply after 2014 rethink

DutchNews, January 24, 2019


There has been a sharp drop in the number of youngsters taking drugs such as ritalin to cope with the symptoms of ADHD, the Dutch pharmaceutical monitoring body has told broadcaster NOS. 

In 2014, nearly 100,000 minors were using the drug, but that had fallen to 78,000 by last year, NOS reported. The number of ritalin users quadrupled between 2003 and 2013.

Concerns about both the diagnosis of ADHD and over-prescribing, led the national health council to sound the alarm in 2014. 

‘That recommendation let in part to doctors and psychiatrists developing a new standard for the diagnosis and treatment of ADHD,’ doctor and ADHD expert Geja Rikkers told the broadcaster. In particular, people with mild symptoms are now less likely to be prescribed the drug.

Related Article:


Thursday, January 24, 2019

French watchdog sounds alert over chemicals in diapers

Yahoo – AFP, January 23, 2019

A French health agency said no medical study had proved health problems caused
by disposable diapers (AFP Photo/JOEL SAGET)

Paris (AFP) - A French public health watchdog issued a warning Wednesday about the risks of several chemicals found in disposable nappies, particularly artificial perfumes, leading the government to demand that manufacturers withdraw them from their products.

The Anses health body stressed there was no medical study which had proved health problems caused by disposable diapers.

But "we cannot exclude a risk... because we have recorded some substances that are above healthy limits," the deputy director of the Agency for Food, Environmental and Occupational Health and Safety (Anses), Gerard Lasfargues, told AFP.

The chemicals identified in the study -- described as the first of its kind -- include two artificial perfumes as well as other complex aromatic products that are refined from oil, and potentially dangerous dioxins.

The French government called a meeting of nappy manufacturers on Wednesday morning and gave them 15 days to remove the products identified by the watchdog.

"I want to reassure parents: Anses says that there is no immediate risk for the health of our children," Health Minister Agnes Buzyn said after the meeting.

"Obviously we should continue putting nappies on our babies. We've been doing that for at least 50 years," she said, while adding that the report does not exclude "a health risk for children in the long term".

"That's why as a precaution we want to protect our children from possible effects," said Buzyn, who met the manufacturers along with the economy and environmental ministers.

In a statement on Wednesday, market leader Pampers, which belongs to US consumer products group Procter & Gamble, said its diapers "are safe and have always been so."

Scientists working for Anses tested 23 types of nappies in real-life conditions as they were worn by children, which it said was a world first.

"We calculated the amount (of chemicals) absorbed, calculated according to the time a nappy is worn, the number of nappies worn by babies, up to 36 months, and then we compared the results with toxicology standards," Lasfargues said.

An average baby in France wears 3,800 to 4,800 nappies, Lasfargues said, with the potentially hazardous chemicals found even in products marketed as environmentally friendly.

Monday, January 21, 2019

'World's oldest man' dies in Japan at 113

Yahoo – AFP, 20 January 2019

Masazo Nonaka enjoyed eating sweets and soaking in a hot spring. He was
awarded the title of oldest man in April

"World's oldest man" Masazo Nonaka, who was born just two years after the Wright brothers launched humanity's first powered flight, died on Sunday aged 113, Japanese media said.

Nonaka was born in July 1905, according to Guinness World Records -- just months before Albert Einstein published his special theory of relativity.

Guinness officially recognised Nonaka as the oldest living man after the death of Spaniard Francisco Nunez Olivera last year.

"We feel shocked at the loss of this big figure. He was as usual yesterday and passed away without causing our family any fuss at all," his granddaughter Yuko told Kyodo News.

Nonaka had six brothers and one sister, marrying in 1931 and fathering five children.

He ran a hot spring inn in his hometown and in retirement enjoyed watching sumo wrestling on TV and eating sweets, according to local media.

Japan has one of the world's highest life expectancies and was home to several people recognised as among the oldest humans to have ever lived.

They include Jiroemon Kimura, the longest-living man on record, who died soon after his 116th birthday in June 2013.

The oldest verified person ever -- Jeanne Louise Calment of France -- died in 1997 at the age of 122, according to Guinness.

Saturday, January 19, 2019

Buried, burned or dissolved? Dutch modernise rules for dealing with the dead

DutchNews, January 18, 2019

Photo: Depositphotos.com

Rules and regulation surrounding burials and cremations will be changed in the coming year to accommodate the wishes of the deceased and the family, home minister Kajsa Ollongren announced on Friday

The introduction of resomation, dissolving the body in liquid, will also be looked at, the minister said. This technique is currently not allowed in the Netherlands but Ollongren has asked the health council to advise on the matter. A report is expected in 2020. 

D66 MP Monica den Boer had earlier asked for the rules to be modernised following signals from families who wanted more freedom of choice when disposing of their loved ones, including the stipulation that bodies be buried after a wait of at least 36 hours after death. 

According to Jewish and Islamic tradition, people should be buried as soon as possible after death. ‘We want all common religions in the Netherlands to be able to practice their beliefs, without having to apply for special procedures,’ Den Boer said at the time. 

Under the new rules this will now be made possible. 

Families also said they objected to the word ‘lijk’, or corpse on the death certificate as ‘unnecessarily hurtful’. This may now be replaced by ‘body’. 

Ashes 

Families will also be able to pick up urns containing the ashes of their relatives from crematoria earlier than the current one-month wait. 

There will also be a solution for crematoria and funeral directors who are left with urns that are not collected by relatives, the minister said. 

What will not be allowed is to bury more than one people in one coffin or to cremate them together. According to the minister that could make it easier to hide a crime. There will also be clearer guidelines about mixing up the ashes of two people, as proposed by D66. 

Friday, January 18, 2019

Babies wanted: Nordic countries crying for kids

Yahoo – AFP, Pierre-Henry DESHAYES with the AFP bureaux in the Nordic region, 17 January 2019

Norway's prime minister has underscored a growing concern: fewer and
fewer babies are being born in Northern Europe

"Norway needs more children! I don't think I need to tell anyone how this is done," Norway's prime minister said cheekily, but she was raising a real concern.

Too few babies are being born in the Nordic region.

The Nordic countries were long a bastion of strong fertility rates on an Old Continent that is rapidly getting older.

But they are now experiencing a decline that threatens their cherished welfare model, which is funded by taxpayers.

"In the coming decades, we will encounter problems with this model," Prime Minister Erna Solberg warned Norwegians in her New Year's speech.

"There will be fewer young people to bear the increasingly heavy burden of the welfare state."

In Norway, Finland and Iceland, birth rates dropped to historic lows in 2017, with 1.49 to 1.71 children born per woman. Just a few years earlier, their birth rates hovered close to the 2.1 level required for their populations to remain stable.

"In all of the Nordic countries, birth rates started dropping in the years after the 2008 financial crisis," University of Oslo sociologist Trude Lappegard told AFP.

"The crisis is over now but it's still falling."

From Copenhagen to the North Cape, from Helsinki to Reykjavik, demographics across the Nordics reveal two things: there are fewer large families, and women are waiting longer before having their first child.

There's no single explanation, but financial uncertainty and a sharp rise in housing costs are seen as likely factors.

An economist in Norway has suggested that women be given 500,000 kroner
(50,000 euros, $58,550) in pension savings for each child born

In the long term, this means there will be fewer people of working age to pay taxes that fund the generous state welfare systems.

These systems pay for, among other things, lengthy parental leaves, which in Sweden can last up to 480 days.

Paying for pregnancies

Experts present differing diagnoses and prescriptions to remedy the situation.

In Norway, one economist concerned about the effect the slowing demographics will have on economic growth has suggested giving women 500,000 kroner (50,000 euros, $58,550) in pension savings for each child born.

Another has suggested that, on the contrary, women in Norway who reach the age of 50 without having had a child should be paid one million kroner, since children also cost society a lot.

Finnish municipalities have already decided to loosen their purse strings to encourage locals to get busy under the covers.

The town of Miehikkala, home to 2,000 people, is offering 10,000 euros for each baby born and raised in the municipality.

"The number of childless individuals is growing rapidly, and the number of women having three or more children is going down. This kind of fall is unheard of in modern times in Finland," said Anna Rotkirch, a family sociologist at the umbrella organisation Finnish Family Federation.

In Denmark, Copenhagen has meanwhile turned its attention to men, who are in less of a hurry to become parents than women, with a campaign aimed at raising awareness about how sperm quality declines with age.

Syrian refugees Walaa Al Hodl,(L), and Kahled Al Hodl applied 
for asylum in Sweden with their six-month-old girl Nour in 2013

Immigration boost

The Nordic region already boasts a wealth of family-friendly initiatives, such as flexible working hours, a vast network of affordable daycares and generous parental leave systems.

But when all that is still not enough to encourage people to have more children, immigration can be a lifeline -- or a threat, depending on the point of view.

Sweden may have a falling birth rate, but it still comes in second in the EU behind France with 1.85 children born per woman in 2016.

That is largely due to Sweden's decades-long history of immigration: immigrant women tend to have more children than the average Swede.

With 2.6 children per woman in recent years, the town of Aneby in southern Sweden has one of the highest rates in the country, a phenomenon attributed to the fact that it opened its doors to immigrants two decades ago.

"Aneby welcomed around 225 Eritreans in the early 1990s and just after that (it took in) refugees from the Balkans. 1994 was a demographic record for the town," local official Ola Gustafsson told AFP.

But population growth among minorities has also fuelled fears.

A former justice minister in Norway, Per-Willy Amundsen of the populist far-right, made headlines when he called for family allowances to be reduced after a third child.

His stated goal was to stop Somalis who, he said, had a higher "birth production" rate than "ethnic Norwegians".
Related Article:

"Recalibration of Free Choice"–  Mar 3, 2012 (Kryon Channelling by Lee Carroll) - (Subjects: (Old) SoulsMidpoint on 21-12-2012, Shift of Human Consciousness, Black & White vs. Color, 1 - Spirituality (Religions) shifting, Loose a Pope “soon”, 2 - Humans will change react to drama, 3 - Civilizations/Population on Earth,  4 - Alternate energy sources (Geothermal, Tidal (Paddle wheels), Wind), 5 – Financials Institutes/concepts will change (Integrity – Ethical) , 6 - News/Media/TV to change, 7 – Big Pharmaceutical company will collapse “soon”, (Keep people sick), (Integrity – Ethical)  8 – Wars will be over on Earth, Global Unity, … etc.) (Text version)

“…  3 - Longer Life is Going to Happen, But…

Here is one that is a review. We keep bringing it up because Humans don't believe it. If you're going to start living longer, there are those who are frightened that there will be overpopulation. You've seen the way it is so far, and the geometric progression of mathematics is absolute and you cannot change it. So if you look at the population of the earth and how much it has shifted in the last two decades, it's frightening to you. What would change that progression?

The answer is simple, but requires a change in thinking. The answer is a civilization on the planet who understands a new survival scenario. Instead of a basic population who has been told to have a lot of children to enhance the race [old survival], they begin to understand the logic of a new scenario. The Akashic wisdom of the ages will start to creep in with a basic survival scenario shift. Not every single woman will look at herself and say, "The clock is ticking," but instead can say, "I have been a mother 14 times in a row. I'm going to sit this one out." It's a woman who understands that there is no loss or guilt in this, and actually feels that the new survival attribute is to keep the family small or not at all! Also, as we have said before, even those who are currently ignorant of population control will figure out what is causing babies to be born [Kryon joke].

Part of the new Africa will be education and healing, and eventually a zero population growth, just like some of the first-world nations currently have. Those who are currently tied to a spiritual doctrine will actually have that doctrine changed (watch for it) regarding Human birth. Then they will be able to make free choice that is appropriate even within the establishment of organized religion. You see, things are going to change where common sense will say, "Perhaps it would help the planet if I didn't have children or perhaps just one child." Then the obvious, "Perhaps I can exist economically better and be wiser with just one. It will help the one!" Watch for these changes. For those of you who are steeped in the tradition of the doctrines and would say that sounds outrageously impossible, I give you the new coming pope [Kryon smile]. For those of you who feel that uncontrolled procreation is inevitable, I encourage you to see statistics you haven't seen or didn't care to look at yet about what first-world countries have already accomplished on their own, without any mandates. It's already happening. That was number three.….”

Saturday, January 12, 2019

Minister to ‘talk to Novartis’ after five-fold cancer drug price hike

DutchNews, January 10, 2019 - By Robin Pascoe

Photo: Depositphotos.com

Health minister Bruno Bruins is planning to talk to Swiss pharmaceuticals giant Novartis this week about the five-fold hike in the price of a drug to treat a rare form of cancer. 

Bruins told a television talk show on Wednesday evening that the decision to put up the price of a year’s supply to €90,000 is an ‘example of how not to behave’. ‘These are outrageous sums,’ Bruins said. ‘And I am not done with this yet.’ 

The drug, lutetium-octreotaat, was developed in the mid 1980s by researchers at Rotterdam’s Erasmus Medical Centre but the company which makes it is now owned by Novartis following a string of takeovers. 

Novartis then registered the drug as an orphan treatment with the European patent office, according to research by Dutch medical journal Nederlands Tijdschrift voorGeneeskunde

Bruins told the Jinek talk show that the EU rules on orphan drugs are meant to stimulate the development of new medicines and says he plans to raise this abuse of the system within Europe. 

‘This expensive medicine is covered in the basic health insurance package so patients will continue to be treated,’ he said. ‘But we are having to deal with so many other really expensive drugs that we really do have to tackle this.’ 

Several Dutch hospitals make their own version of lutetium-octreotaat at a cost of some €4,000 per drip. A full treatment session comprises four drips. Apple chief Steve Jobs was among the patients who were treated using the medicine in Rotterdam. 

Meeting

A spokeswoman for Novartis told DutchNews.nl that the company is ‘willing to discusses this topic with all stakeholders including the government’. 

The company said the until its approval by the European Medicines Agency, the drug, formally known as Lutathera, ‘was only available as an experimental treatment at centers with the facilities and capabilities to manage the compounding of a radioactive product.’ 

The drug has now undergone major clinical trials and is available as a targeted therapy to patients in Europe and the US, Novartis said. 

After its approval in 2018, ‘the price of Lutathera was carefully considered and based on the relative benefit it provides to patients’, the company said. 

Price

Last year, the Dutch healthcare institute Zorginstituut Nederland said insurers should stop paying for expensive drugs if pharmaceutical companies continue to refuse to say how they arrive at the price.

And in November, Amsterdam’s AMC teaching hospital was given the green light by health ministry inspectors to make its own version of a licenced drug to treat a rare metabolic disorder. 

The hospital began making its own version of the drug after manufacturer Leadiant ramped up the price by around 500% to €200,000 per patient per year. 

The drug has been available since the 1970s but Leadiant only registered it as an orphan medicine with the European medicines agency in 2017. 

Orphan status, given to drugs which are used to treat very specific and rare illnesses, means a drug cannot be copied commercially for a 10-year period.

Related Article:


Tuesday, January 8, 2019

Eli Lilly to acquire Loxo Oncology for $8 billion

Yahoo – AFP, January 7, 2019

An employee works in an unit dedicated to the production of insulin pens at the
factory run by pharmaceutical company Eli Lilly in Fegersheim, eastern France,
on October 12, 2015

Washington (AFP) - Pharmaceutical giant Eli Lilly will acquire cancer treatment specialist Loxo Oncology in a cash deal valued at around $8 billion, the companies said on Monday.

The firms "announced a definitive agreement for Lilly to acquire Loxo Oncology for $235.00 per share in cash, or approximately $8.0 billion," a statement said.

The deal -- which represents a premium of some 68 percent over Loxo Oncology's closing share price on Friday -- is expected to close by the end of the first quarter, the statement said.

The announcement is the latest in a series of major pharmaceutical deals: last week, Bristol-Myers Squibb said it would buy biotech firm Celgene in a $74 billion cash-and-stock agreement, creating a rival to the world's largest drug makers.

Other recent large pharma deals include French company Sanofi's purchase of US hemophilia group Bioverativ for $11.6 billion and Novartis' $8.7 billion acquisition of rare-disease treatment company AveXis.

Sunday, January 6, 2019

Bristol-Myers to face suit over US syphilis experiment in Guatemala

Yahoo – AFP, January 5, 2019

Bristol-Myers Squibb is among those ordered by a US judge to face a $1 billion
lawsuit launched in 2015 by 774 Guatemalan victims and relatives over an expriment
in 1940s which aimed to find out if penicillin could be used to prevent STDs (AFP
Photo/GEORGES GOBET)

Washington (AFP) - A US federal judge has ruled pharmaceutical company Bristol-Myers Squibb, Johns Hopkins University and the Rockefeller Foundation must face a $1 billion lawsuit over their roles in a 1940s medical experiment that saw hundreds of Guatemalans infected with syphilis.

774 Guatemalan victims and relatives in 2015 launched a civil suit over the US-led experiment, which aimed to find out if penicillin could be used to prevent sexually transmitted diseases.

They claimed the experiment "subjected them or their family members to medical experiments in Guatemala without their knowledge or consent during the 1940s and 1950s."

US District Judge Theodore Chuang rejected arguments from the defense that a recent Supreme Court decision protecting foreign companies from US lawsuits over human rights abuses abroad also applied to domestic firms.

The judge said allowing the case to move forward would "promote harmony" by giving the foreign plaintiffs the opportunity to seek justice in US courts.

The unethical experiment was revealed by Doctor Susan Reverby, a professor at Wellesley College in the US.

She came across the work while researching notes left by John Charles Cutler, a public health services sexual disease specialist who headed up the experiment, following his death in 2003.

Cutler and his fellow researchers enrolled soldiers, mental patients, prostitutes, convicts and others in Guatemala for the study.

Former US president Barack Obama apologized for the experiments in 2010, while his Secretary of State Hillary Clinton described the experiments as "clearly unethical."

Saturday, January 5, 2019

People with Down ‘never stop learning’, US-Dutch research shows

DutchNews, January 4, 2019

Photo: Depositphotos.com

People with Down syndrome never stop learning and continue to acquire functional skills well into adulthood, according to a new mass study by US and Dutch researchers. 

The research is based on the experiences of more than 2,600 families in the US and the Netherlands and coordinated by researchers from the Dutch Down Syndrome Foundation and the Massachussetts General Hospital. 

‘Contrary to some public beliefs, people with Down syndrome never stop learning, and functional skills can still be attained and improved well into adulthood,’ director of the programme Brian Skotko told the Harvard Gazette

The results in both the US – based on questionnaires in 2008 and 2009 – and the Netherlands (questionnaire in 2016) were broadly similar. They indicated that most people with Down syndrome could walk by 25 months of age, speak reasonably well by age 12, maintain personal hygiene by 13, and work independently by 20. 

By the age of 31, 49% were reading reasonably well, 46%  could write reasonably well, 34% were living independently, and around 30% could travel independently. 

‘Now we have guideposts — based on the responses of thousands of parents — that can help clinicians know when children may be falling behind their peers with Down syndrome and, when necessary, refer parents to additional supports, resources, and therapies,’ Skotko said.

Wednesday, January 2, 2019

Irish woman who fought Dutch hospital secrecy dies of cancer

DutchNews, January 1, 2019

Adrienne Cullen, the Irish woman who campaigned for transparency in hospital care after she was left with terminal cervical cancer thanks to a Dutch medical error has died at the age of 58. 

Her husband Peter Cluskey issued a statement on Twitter saying that his wife had been ‘appallingly treated’ and that this had made her a ‘formidable warrior’. 


Adrienne first underwent tests in the Netherlands in 2011 but it was not until two years later that a review of old pathology results showed that she had cancer. By 2015 her cancer had spread and, because of the delays, was classed terminal. 

She was offered €500,000 compensation by Utrecht’s UMCU teaching hospital on condition she sign a gagging order, which she refused to do, and began campaigning for more transparency about medical errors. 

The hospital eventually settled with Adrienne and her husband for €545,000, the highest medical negligence award ever made in the Netherlands. 

Lecture

In April this year, she was able to give a lecture at the hospital calling for the victims of medical errors to be heard, alongside the doctor responsible for her misdiagnosis. An Adrienne Cullen lecture is now part of the university calendar. 

Early in December she was given an honorary doctorate by the University of Cork. Her book about her experiences ‘Deny, Dismiss, Dehumanize : What Happened When I went to Hospital’ will be published shortly. Adrienne’s impact was such in the Netherlands that public broadcaster NOS and the NRC newspaper are among the media outlets to carry an obituary.