Google – AFP, Olivier Thibault (AFP), 12 November 2012
 |
Japanese
Kyoto University professor Shinya Yamanaka (AFP, Patrick Kovarik)
|
PARIS —
Newly-crowned Nobel laureate Shinya Yamanaka on Monday cautioned that stem
cells could still spur sharp debate, despite his achievement in creating cells
that are not derived from embryos.
The
Japanese scientist was interviewed on a trip to Paris after co-winning the 2012
Nobel Prize for Medicine last month alongside Britain's John Gurdon.
Yamanaka
was lauded for "reprogramming" mature cells so that they return to a
versatile primitive state, called stem cells.
Researchers
hope that stem cells may one day provide lab-grown tissue to replenish organs
damaged by accident or disease.
Only the
very first steps have been taken along this road, but the mission has been
boosted by Yamanaka's work, for it implies that stem cells culled from embryos
-- until now the most potent but also a highly controversial source -- may no
longer be needed.
But
Yamanaka warned that his induced pluripotent stem cells (iPS) are unlikely to
escape a storm touching on the creation of life.
"Now
we can avoid the use of human embryos, so it's good. However, we are facing new
ethical issues," he told AFP.
The
question, he said, lies with the creation of so-called germ cells -- cells that
give rise to sperm or eggs.
"Can
we make sperm from blood and can we fertilise these oocytes (eggs)?" he
asked. "We really need discussion in society about how much we can do
about this new technology."
Yamanaka
said scientists in Kobe had already applied to the Japanese authorities for
permission to carry out the world's first iPS trial on humans, using cells on
patients suffering from retinal disease.
And, he
said, Japan was pushing ahead with a stem cell bank, which was approved in
July.
"In
theory, we can make iPS cells from each patient. But it would be very expensive
and take six months to prepare the cells from each patient. So in reality, we
cannot do that," he said.
A stem cell
bank would be a good alternative, said Yamanaka.
The idea is
to choose donors whose DNA profile is least likely to trigger rejection by a
patient's immune system.
"We
may be able to cover many patients by having only a handful of iPS stock,
that's our plan," he said. "By our estimations, we identified 140
such specific donors, (and with these) we could cover up to 90 percent of the
whole population."
Some
scientists have been cautious about iPS technology, fearing that reprogramming
errors as an adult cell is rewound to its infant state, using a batch of
introduced genes, could cause tumours.
Yamanaka,
50, carried out his groundbreaking work in 2007, but was quick to pay tribute
to Gurdon, who laid the conceptual foundations in 1962.
In 2007,
"We thought maybe we will win the Nobel prize in the future if it
goes" to clinical trials, he said.
"So we
did not expect (it) at this time because it was too early. But we were awarded
because of Sir John Gurdon and his discovery 50 years ago... Because of him I
was very lucky to be awarded."
Related Articles:
"Recalibration of Knowledge" – Jan 14, 2012 (Kryon channelled by Lee Carroll) - (Subjects: Channelling, God-Creator, Benevolent Design, New Energy, Shift of Human Consciousness, (Old) Souls, Reincarnation, Gaia, Old Energies (Africa,Terrorists, Cuba, Iran, North Korea, Venezuela ... ), Weather, Rejuvenation, Akash, Nicolas Tesla / Einstein, Cold Fusion, Magnetics, Lemuria, Atomic Structure (Electrons, Particles, Polarity, Self Balancing, Magnetism, Higgs Boson), Entanglement, "Life is necessary for a Universe to exist and not the other way around", DNA, Humans (Baby getting ready, First Breath, Stem Cells, Embryonic Stem Cells, Rejuvenation), Global Unity, ... etc.) - (Text Version)
”… There are several things that are going to happen in mainstream science. First, you're going to find some secrets of DNA and they're going to be embryonic. Start watching scientists discover the embryonic cells and the magic within them. You already know that unusual stem cells exist in the placenta. You also know that the pre-programmed adult stem cells are still there in the body. But what about the DNA of the unborn? (Intellectuals, please keep reading, for to stop now will create unrest.) Second, your work today Yawee, will represent "the perfect template" without using what you did in Lemuria. That's why you're the Human who will do this. It's an extension of why you came here, and is perfect for 2012 and beyond.
These embryonic cells of the unborn are untouchable by society, and they might as well be on Mars, for no science is going to try to use these cells in a 3D manner, which is all you know how to do at this point. If they try, it won't work anyway. There are quantum processes you are learning about that are not only non-invasive, but actually helpful and that can transfer attributes from one biological cell to another and from one Human to another. Think "wireless" [Kryon human again]. What you thought would take wires over 1,000 miles long is now done with satellites. It's an analogy that shows you that you are moving into totally new understandings of the transfer of energy. Let's discuss the mother in that temple for a moment. …”
These embryonic cells of the unborn are untouchable by society, and they might as well be on Mars, for no science is going to try to use these cells in a 3D manner, which is all you know how to do at this point. If they try, it won't work anyway. There are quantum processes you are learning about that are not only non-invasive, but actually helpful and that can transfer attributes from one biological cell to another and from one Human to another. Think "wireless" [Kryon human again]. What you thought would take wires over 1,000 miles long is now done with satellites. It's an analogy that shows you that you are moving into totally new understandings of the transfer of energy. Let's discuss the mother in that temple for a moment. …”
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